Temporal Evolution of Predictive Factors for Heart Disease: A Random Forest Analysis
DOI:
https://doi.org/10.61173/rfp4zs80Keywords:
Feature importance, random forest, disease prediction, machine learningAbstract
Heart disease remains the leading cause of death globally, profoundly affecting patients’ quality of life and placing a significant burden on healthcare systems and society. Identifying and understanding the key factors associated with heart disease is essential for its prevention, diagnosis, and treatment. This study explores how the significance of these factors has evolved over time by analyzing data from the Behavioral Risk Factor Surveillance System (BRFSS) from 2015 to 2021. This study focused on lifestyle and demographic variables for non-institutionalized adults aged 18 and older, selecting 36 relevant variables from an initial pool of over 300 each year through rigorous data cleaning and normalization. Utilizing a random forest algorithm, this paper evaluated feature importance across the years. The findings consistently highlight BMI, Income, Age, General Health, Education, and Smoking as pivotal predictors of myocardial infarction (MI) and coronary heart disease (CHD). Although High Cholesterol and Arthritis appeared in the top ten features only once during the four years, they maintained a notable presence within the top fifteen, indicating their significant but secondary role compared to the consistently prominent factors. This variability highlights that while some factors retain stable importance, others may vary in relevance due to changing health trends and dataset characteristics.References
in maintaining overall health. In 2019, High Cholesterol (Basel). 2020;20(7):2136. appeared among the top ten features, highlighting its rel- [4] McKinney SM, Sieniek M, Godbole V, Godwin J, Antropova
evance in assessing heart disease risk. Similarly, in 2021, N, Ashrafian H, et al. International evaluation of an AI system Arthritis made it into the top ten. Although both High for breast cancer screening. Nature. 2020;577(7788):89-94. Cholesterol and Arthritis appeared in the top ten only once [5] Korolev IO, Symonds LL, Bozoki AC. Predicting progression across the four years, they consistently ranked within the from mild cognitive impairment to Alzheimer’s dementia using top fifteen, reflecting their significant but somewhat sec- clinical, MRI, and plasma biomarkers via probabilistic pattern ondary role compared to the more consistently prominent classification. PLOS ONE. 2016;11(2) features. This variability suggests that while certain fac- [6] Centers for Disease Control and Prevention. Behavioral Risk
tors maintain consistent importance, others may fluctuate Factor Surveillance System annual survey data. 2015. Available in relevance based on evolving health trends and dataset from: https://www.cdc.gov/brfss/annual_data/annual_data.htm characteristics. [7] Codecademy Team. Deep learning workflow. Codecademy. 2024, Available from: https://www.codecademy.com/learn/paths/ deep-learning 4. Conclusion [8] Géron A. Hands-On Machine Learning with Scikit-Learn, This article explores how the ranking of important fac- Keras, and TensorFlow: Concepts, Tools, and Techniques to tors related to heart disease has changed over time. Using Build Intelligent Systems. O’Reilly Media; 2019. data from the Behavioral Risk Factor Surveillance Sys- [9] Liaw A, Wiener M. Classification and regression by tem (BRFSS), which includes lifestyle and demographic randomForest. R News. 2002;2(3):18-22. Available from: https:// variables for non-institutionalized adults aged 18 and cran.r-project.org/doc/Rnews/Rnews_2002-3.pdf
older from 2015 to 2021. This study selected 36 relevant [10] Rashmi S, Kumar P, Reddy K. Feature selection and variables out of over 300 per year, removing rows with classification of heart disease using machine learning algorithms. J Healthc Eng. 2021;2021:8834729.
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